en بهداشت Health تحقیقی Original article <div style="text-align: justify;"><span style="font-size:14px;"><span style="line-height:2;"><span sans-serif="" style="font-family:Calibri,"><b><i><span new="" roman="" style="font-family:" times="">Background and <span style="color:black">Objectives:</span></span></i></b> <span new="" roman="" style="font-family:" times=""><span style="color:black">Xerostomia has been defined as the dry mouth sensation due to hyposalivation or change in saliva composition. Many herbal medicines have been used as treatment options. Since the combination of aloe vera extract and honey, and Lemon is suggested as a potent oral moisturizer, limited studies have been done in this field. Therefore, we decided to compare the effects of these two moisturizers in cases of xerostomia.</span></span></span><br> <span sans-serif="" style="font-family:Calibri,"><b><i><span new="" roman="" style="font-family:" times=""><span style="color:black">Material and Methods:</span></span></i></b><span new="" roman="" style="font-family:" times=""><span style="color:black"> a </span></span><span lang="EN-GB"><span new="" roman="" style="font-family:" times=""><span style="color:black">combination of aloe vera extract and honey, lemon extract, and placebo mouthwashes were provided to 30 participants suffering from xerostomia. Each patient used three types of mouthwash in the following order: For the first mouthwash, the patients were asked to express their sensation of dry mouth using VAS on the first, third, and fifth days. This was followed by a one-week rest period in which patients did not use mouthwash. The same process was repeated to measure the second and third mouthwashes.</span></span></span><b><i><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></i></b></span><br> <span sans-serif="" style="font-family:Calibri,"><b><i><span new="" roman="" style="font-family:" times=""><span style="color:black">Results: </span></span></i></b><span new="" roman="" style="font-family:" times=""><span style="color:black">Lemon and a combination of aloe vera extract and honey were both found to be significantly effective in reducing the dry mouth sensation. However, lemon was significantly more effective in this regard. Placebo was significantly less effective than both extracts and overall had no statistically significant impact on the dry mouth sensation (p<0.001)<b><i></i></b></span></span></span><br> <span sans-serif="" style="font-family:Calibri,"><b><i><span new="" roman="" style="font-family:" times=""><span style="color:black">Conclusion:</span></span></i></b> <span new="" roman="" style="font-family:" times="">Lemon mouthwash was significantly more effective than a combination of aloe vera and honey. Thus, it is recommended to improve dry mouth sensation.</span><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></span><br> <span style="font-family:Times New Roman;"><span style="font-size:14px;"><span style="line-height:115%"><span style="line-height:115%"><span style="color:black"></span></span></span></span></span></div> Xerostomia,Aloe,Wetting Agents,Citrus, 51 60 http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-864-2&slc_lang=en&sid=1 Leila Rajaei-Behbahani Leila.rajaei@gmail.com 10031947532846008386 10031947532846008386 No Oral & Maxillofacial medicine department, Faculty of Dentistry, Ahwaz University of medical sciences, Ahwaz, Iran Shahla Afshar Shahlaafshar388@gmail.com 10031947532846008387 10031947532846008387 No Oral & Maxillofacial medicine specialist, Tehran, Iran Sara Rajaei-Behbahani Sara.rajaeii@gmail.com 10031947532846008388 10031947532846008388 No Dentist, Ahwaz,Iran Maryam-Sadat Sadrzadeh-afshar m_sadrzade@alumnus.tums.ac.ir 10031947532846008389 10031947532846008389 Yes Oral & Maxillofacial medicine department, Faculty of Dentistry, Aja University of medical sciences, Tehran, Iran